Clinical Trial Tracker

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io.github.agentstructure/clinicalv1.0.0

Search and monitor ClinicalTrials.gov and EU trial registry records, with trial change tracking and

Health & Science

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compare_clinical_trials Read-only

Side-by-side registry attributes for 2 to 5 studies. A structural comparison only, never an efficacy or safety ranking.

nct_idsarray, required

Tools (7)

compare_clinical_trials

Side-by-side registry attributes for 2 to 5 studies. A structural comparison only, never an efficacy or safety ranking.

read-only

Argument	Type	Description
nct_ids*	array

Input schema (JSON)

{
  "type": "object",
  "required": [
    "nct_ids"
  ],
  "properties": {
    "nct_ids": {
      "type": "array",
      "items": {
        "type": "string",
        "pattern": "^NCT\\d{8}$"
      },
      "maxItems": 5,
      "minItems": 2
    }
  },
  "additionalProperties": false
}

get_clinical_trial

One study by NCT id: full structured record (status, dates, enrollment, eligibility text, sites and contacts, outcomes, documents), plus the changes AgentStructure has observed and data freshness.

read-only

Argument	Type	Description
nct_id*	string
max_locations	integer
location_filter	object

Input schema (JSON)

{
  "type": "object",
  "required": [
    "nct_id"
  ],
  "properties": {
    "nct_id": {
      "type": "string",
      "pattern": "^NCT\\d{8}$"
    },
    "max_locations": {
      "type": "integer",
      "maximum": 200,
      "minimum": 0
    },
    "location_filter": {
      "type": "object",
      "properties": {
        "city": {
          "type": "string",
          "maxLength": 80,
          "minLength": 1
        },
        "state": {
          "type": "string",
          "maxLength": 80,
          "minLength": 1
        },
        "country": {
          "type": "string",
          "maxLength": 80,
          "minLength": 1
        }
      },
      "additionalProperties": false
    }
  },
  "additionalProperties": false
}

get_trial_changes

The change history AgentStructure recorded for a study: previous and new values, event type, dates and provenance. Starts monitoring the study if it was unknown.

read-only

Argument	Type	Description
limit	integer
since	string
nct_id*	string
event_types	array
include_baseline	boolean

Input schema (JSON)

{
  "type": "object",
  "required": [
    "nct_id"
  ],
  "properties": {
    "limit": {
      "type": "integer",
      "maximum": 200,
      "minimum": 1
    },
    "since": {
      "type": "string",
      "pattern": "^\\d{4}-\\d{2}-\\d{2}$"
    },
    "nct_id": {
      "type": "string",
      "pattern": "^NCT\\d{8}$"
    },
    "event_types": {
      "type": "array",
      "items": {
        "enum": [
          "STUDY_FIRST_OBSERVED",
          "NEW_STUDY_REGISTERED",
          "NEW_STUDY_MATCHED",
          "NOT_RECRUITING_TO_RECRUITING",
          "RECRUITING_TO_SUSPENDED",
          "RECRUITMENT_CLOSED",
          "STUDY_SUSPENDED",
          "STUDY_TERMINATED",
          "STUDY_WITHDRAWN",
          "STUDY_COMPLETED",
          "STATUS_CHANGED",
          "NEW_SITE_ADDED",
          "SITE_REMOVED",
          "SITE_STATUS_CHANGED",
          "ENROLLMENT_TARGET_CHANGED",
          "ENROLLMENT_ACTUAL_REPORTED",
          "START_DATE_REVISED",
          "PRIMARY_COMPLETION_DATE_REVISED",
          "COMPLETION_DATE_REVISED",
          "DATE_CONFIRMED_ACTUAL",
          "RESULTS_POSTED",
          "PHASE_CHANGED",
          "ELIGIBILITY_CHANGED",
          "SPONSOR_CHANGED",
          "COLLABORATORS_CHANGED",
          "INTERVENTIONS_CHANGED",
          "CONDITIONS_CHANGED",
          "TITLE_CHANGED",
          "STUDY_TYPE_CHANGED",
          "FDA_RECALL_POSTED",
          "FDA_APPROVAL_RECORDED",
          "FDA_SUPPLEMENT_APPROVED",
          "FDA_LABEL_UPDATED",
          "PUBLICATION_LINKED"
        ],
        "type": "string"
      },
      "maxItems": 40
    },
    "include_baseline": {
      "type": "boolean"
    }
  },
  "additionalProperties": false
}

get_trial_intelligence_brief

A source-linked brief on a study, sponsor, condition, intervention, or one of your watchlists: current facts, observed developments, unknowns, and freshness.

read-only

Argument	Type	Description
value*	string	NCT id, sponsor, condition, intervention, or watchlist id
subject*	string

Input schema (JSON)

{
  "type": "object",
  "required": [
    "subject",
    "value"
  ],
  "properties": {
    "value": {
      "type": "string",
      "maxLength": 200,
      "minLength": 1,
      "description": "NCT id, sponsor, condition, intervention, or watchlist id"
    },
    "subject": {
      "enum": [
        "study",
        "sponsor",
        "condition",
        "intervention",
        "watchlist"
      ],
      "type": "string"
    }
  },
  "additionalProperties": false
}

search_clinical_trials

Search ClinicalTrials.gov by condition, intervention, sponsor, phase, recruitment status, location, institution, study type or dates. Returns structured studies with source links and retrieval time.

read-only

Argument	Type	Description
near	object
phase	array
query	string	Free-text search across the registry
nct_ids	array
sponsor	string	Sponsor or collaborator name
location	string	Free-text place, e.g. 'Boston, Massachusetts'
condition	string	Disease or condition, e.g. multiple sclerosis
page_size	integer
page_token	string
study_type	string

search_eu_trials

Search the EU Clinical Trials Information System (CTIS, euclinicaltrials.eu) by condition, medicine, sponsor or text, or get one trial by EU CT number (with its ClinicalTrials.gov link when listed). Experimental source.

read-only

Argument	Type	Description
page	integer
query	string	Free text across EU trial records
sponsor	string
medicine	string	Medicine or active substance
condition	string	Medical condition
ct_number	string	Get one trial by EU CT number
page_size	integer

Input schema (JSON)

{
  "type": "object",
  "properties": {
    "page": {
      "type": "integer",
      "maximum": 100,
      "minimum": 1
    },
    "query": {
      "type": "string",
      "maxLength": 200,
      "minLength": 1,
      "description": "Free text across EU trial records"
    },
    "sponsor": {
      "type": "string",
      "maxLength": 200,
      "minLength": 1
    },
    "medicine": {
      "type": "string",
      "maxLength": 200,
      "minLength": 1,
      "description": "Medicine or active substance"
    },
    "condition": {
      "type": "string",
      "maxLength": 200,
      "minLength": 1,
      "description": "Medical condition"
    },
    "ct_number": {
      "type": "string",
      "pattern": "^\\d{4}-\\d{6}-\\d{2}-\\d{2}$",
      "description": "Get one trial by EU CT number"
    },
    "page_size": {
      "type": "integer",
      "maximum": 50,
      "minimum": 1
    }
  },
  "additionalProperties": false
}

search_fda_updates

Search openFDA: Drugs@FDA approvals (drug/drugsfda), recalls (drug/enforcement) or labeling (drug/label) by drug, firm, application number or date.

read-only

Argument	Type	Description
drug	string
firm	string
limit	integer
since	string
until	string
dataset*	string	drug/drugsfda = approvals; drug/enforcement = recalls; drug/label = labeling
application_number	string

Input schema (JSON)

{
  "type": "object",
  "required": [
    "dataset"
  ],
  "properties": {
    "drug": {
      "type": "string",
      "maxLength": 120,
      "minLength": 1
    },
    "firm": {
      "type": "string",
      "maxLength": 120,
      "minLength": 1
    },
    "limit": {
      "type": "integer",
      "maximum": 50,
      "minimum": 1
    },
    "since": {
      "type": "string",
      "pattern": "^\\d{4}-\\d{2}-\\d{2}$"
    },
    "until": {
      "type": "string",
      "pattern": "^\\d{4}-\\d{2}-\\d{2}$"
    },
    "dataset": {
      "enum": [
        "drug/enforcement",
        "drug/drugsfda",
        "drug/label"
      ],
      "type": "string",
      "description": "drug/drugsfda = approvals; drug/enforcement = recalls; drug/label = labeling"
    },
    "application_number": {
      "type": "string",
      "pattern": "^(NDA|ANDA|BLA)\\d{6}$"
    }
  },
  "additionalProperties": false
}

{ "type": "object", "properties": { "near": { "type": "object", "required": [ "latitude", "longitude", "radius_miles" ], "properties": { "latitude": { "type": "number", "maximum": 90, "minimum": -90 }, "longitude": { "type": "number", "maximum": 180, "minimum": -180 }, "radius_miles": { "type": "number", "maximum": 500, "minimum": 1 } }, "additionalProperties": false }, "phase": { "type": "array", "items": { "enum": [ "NA", "EARLY_PHASE1", "PHASE1", "PHASE2", "PHASE3", "PHASE4" ], "type": "string" }, "maxItems": 6 }, "query": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Free-text search across the registry" }, "nct_ids": { "type": "array", "items": { "type": "string", "pattern": "^NCT\\d{8}$" }, "maxItems": 50, "minItems": 1 }, "sponsor": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Sponsor or collaborator name" }, "location": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Free-text place, e.g. 'Boston, Massachusetts'" }, "condition": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Disease or condition, e.g. multiple sclerosis" }, "page_size": { "type": "integer", "maximum": 50, "minimum": 1 }, "page_token": { "type": "string", "maxLength": 500 }, "study_type": { "enum": [ "INTERVENTIONAL", "OBSERVATIONAL", "EXPANDED_ACCESS" ], "type": "string" }, "institution": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Research site / facility name" }, "intervention": { "type": "string", "maxLength": 200, "minLength": 1, "description": "Drug or other intervention name" }, "start_date_to": { "type": "string", "pattern": "^\\d{4}-\\d{2}-\\d{2}$" }, "updated_since": { "type": "string", "pattern": "^\\d{4}-\\d{2}-\\d{2}$" }, "location_filter": { "type": "object", "properties": { "city": { "type": "string", "maxLength": 80, "minLength": 1 }, "state": { "type": "string", "maxLength": 80, "minLength": 1 }, "country": { "type": "string", "maxLength": 80, "minLength": 1 } }, "description": "Show only sites in this city/state/country in each result", "additionalProperties": false }, "start_date_from": { "type": "string", "pattern": "^\\d{4}-\\d{2}-\\d{2}$" }, "first_posted_since": { "type": "string", "pattern": "^\\d{4}-\\d{2}-\\d{2}$" }, "recruitment_status": { "type": "array", "items": { "enum": [ "ACTIVE_NOT_RECRUITING", "COMPLETED", "ENROLLING_BY_INVITATION", "NOT_YET_RECRUITING", "RECRUITING", "SUSPENDED", "TERMINATED", "WITHDRAWN", "AVAILABLE", "NO_LONGER_AVAILABLE", "TEMPORARILY_NOT_AVAILABLE", "APPROVED_FOR_MARKETING", "WITHHELD", "UNKNOWN" ], "type": "string" }, "maxItems": 14 } }, "additionalProperties": false }